Merge pull request #29756 from geneontology/issue-29746

Revised 7 terms, #29746
geneontology · Feb 20, 2025 · c3687fe · c3687fe
2 parents 99d3977 + 6c98565
commit c3687fe
Showing 1 changed file with 30 additions and 20 deletions.
diff --git a/src/ontology/go-edit.obo b/src/ontology/go-edit.obo
@@ -16343,14 +16343,14 @@ creation_date: 2010-02-09T10:50:59Z
 
 [Term]
 id: GO:0002161
-name: aminoacyl-tRNA editing activity
+name: aminoacyl-tRNA deacylase activity
 namespace: molecular_function
 def: "The hydrolysis of an incorrectly aminoacylated tRNA." [GOC:hjd, PMID:14663147, PMID:16087889]
 synonym: "amino acid proofreading activity" RELATED []
 synonym: "aminoacyl-tRNA hydrolysis activity" RELATED []
-is_a: GO:0052689 ! carboxylic ester hydrolase activity
 is_a: GO:0140101 ! catalytic activity, acting on a tRNA
 relationship: part_of GO:0106074 ! aminoacyl-tRNA metabolism involved in translational fidelity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
 created_by: hjd
 creation_date: 2010-02-12T03:06:56Z
 
@@ -16698,10 +16698,11 @@ creation_date: 2011-08-31T02:20:06Z
 
 [Term]
 id: GO:0002196
-name: Ser-tRNA(Ala) hydrolase activity
+name: Ser-tRNA(Ala) deacylase activity
 namespace: molecular_function
 def: "Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala)." [GOC:hjd, PMID:21285375]
-is_a: GO:0002161 ! aminoacyl-tRNA editing activity
+is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
 created_by: hjd
 creation_date: 2011-09-30T02:18:50Z
 
@@ -34658,22 +34659,22 @@ is_a: GO:0016763 ! pentosyltransferase activity
 
 [Term]
 id: GO:0004045
-name: aminoacyl-tRNA hydrolase activity
+name: peptidyl-tRNA hydrolase activity
 namespace: molecular_function
 alt_id: GO:0019850
 alt_id: GO:0019851
-def: "Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA." [EC:3.1.1.29]
+def: "Catalysis of the reaction: an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H+." [RHEA:54448]
 synonym: "aminoacyl-transfer ribonucleate hydrolase activity" RELATED [EC:3.1.1.29]
 synonym: "aminoacyl-tRNA aminoacylhydrolase activity" RELATED [EC:3.1.1.29]
 synonym: "aminoacyl-tRNA hydrolase reaction" EXACT []
 synonym: "D-tyrosyl-tRNA hydrolase activity" NARROW [PMID:15292242]
 synonym: "N-substituted aminoacyl transfer RNA hydrolase activity" RELATED [EC:3.1.1.29]
-synonym: "peptidyl-tRNA hydrolase activity" RELATED [EC:3.1.1.29]
 xref: EC:3.1.1.29
 xref: MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN
-xref: RHEA:54448
+xref: RHEA:54448 {source="skos:exactMatch"}
 is_a: GO:0052689 ! carboxylic ester hydrolase activity
 is_a: GO:0140101 ! catalytic activity, acting on a tRNA
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
 
 [Term]
 id: GO:0004046
@@ -252521,22 +252522,26 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i
 
 [Term]
 id: GO:0043906
-name: Ala-tRNA(Pro) hydrolase activity
+name: Ala-tRNA(Pro) deacylase activity
 namespace: molecular_function
 def: "Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro)." [GOC:jl, PMID:14663147]
 synonym: "Ala-tRNAPro hydrolase activity" EXACT []
-is_a: GO:0002161 ! aminoacyl-tRNA editing activity
+is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
 property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21843" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
 
 [Term]
 id: GO:0043907
-name: Cys-tRNA(Pro) hydrolase activity
+name: Cys-tRNA(Pro) deacylase activity
 namespace: molecular_function
-def: "Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro)." [GOC:jl, PMID:15886196]
+def: "Catalysis of the reaction: L-cysteinyl-tRNA(Pro) + H2O = tRNA(Pro) + L-cysteine + H+." [GOC:jl, PMID:15886196, RHEA:25351]
 synonym: "Cys-tRNA(Pro) deacetylase activity" EXACT []
 synonym: "Cys-tRNAPro hydrolase activity" EXACT []
-is_a: GO:0002161 ! aminoacyl-tRNA editing activity
+xref: EC:3.6.1.n2
+xref: RHEA:25351 {source="skos:exactMatch"}
+is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
 property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21843" xsd:anyURI
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
 
 [Term]
 id: GO:0043908
@@ -326086,7 +326091,7 @@ def: "Catalysis of the reaction: a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid
 xref: EC:3.1.1.96
 xref: MetaCyc:RXN-15041
 xref: RHEA:13953 {source="skos:exactMatch"}
-is_a: GO:0002161 ! aminoacyl-tRNA editing activity
+is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
 is_a: GO:0052689 ! carboxylic ester hydrolase activity
 is_a: GO:0160215 ! deacylase activity
 
@@ -440222,10 +440227,13 @@ creation_date: 2017-05-24T19:37:50Z
 
 [Term]
 id: GO:0106026
-name: Gly-tRNA(Ala) hydrolase activity
+name: Gly-tRNA(Ala) deacylase activity
 namespace: molecular_function
-def: "Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala)." [PMID:28362257]
-is_a: GO:0002161 ! aminoacyl-tRNA editing activity
+def: "Catalysis of the reaction: glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H+." [PMID:28362257, RHEA:53744]
+xref: EC:3.1.1.96 {source="skos:broadMatch"}
+xref: RHEA:53744 {source="skos:exactMatch"}
+is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
 created_by: hjd
 creation_date: 2017-06-16T17:13:33Z
 
@@ -440958,11 +440966,13 @@ creation_date: 2018-03-06T15:54:33Z
 
 [Term]
 id: GO:0106105
-name: Ala-tRNA(Thr) hydrolase activity
+name: Ala-tRNA(Thr) deacylase activity
 namespace: molecular_function
-def: "Catalysis of the hydrolysis of misacylated ala-tRNA(thr)." [PMID:29410408]
+def: "Catalysis of the reaction: L-alanyl-tRNA(Thr) + H2O = tRNA(Thr) + L-alanine + H+." [PMID:29410408, RHEA:17793]
 synonym: "L-alanyl-tRNA(Thr) deacylase" EXACT []
-is_a: GO:0002161 ! aminoacyl-tRNA editing activity
+xref: RHEA:17793 {source="skos:exactMatch"}
+is_a: GO:0002161 ! aminoacyl-tRNA deacylase activity
+property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29746" xsd:anyURI
 created_by: hjd
 creation_date: 2018-03-14T22:03:29Z