Exploring ACE2 and NRP1 expression patterns on healthy human heart left ventricle (publicly available 10X Visium data).
ACE2 transcript encodes for SARS-CoV2 receptor on host cells, and NRP1 encodes for a host protein potentiating SARS-CoV-2 infectivity.
- 1st-2nd row: visualizing expression per gene, co-expression spots of ACE2+ and NRP1+
- 3rd row: mean co-expression of ACE2+ and NRP1+
Rmd script using Seurat, Plotly, Fields, spatstat, and other cool packages.