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9e39f0f · May 18, 2020

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docking

The covid19-SARS-CoV-2 Docking repository

Currently covered are ligands and receptors related to:

  • alpha ketoamide inihibitors
  • spike protein inhibitors (sweetlead)
  • PanDDA library targets
  • N3-Mpro main protease
  • ligands-global (a collection of SARS and SARS-Cov-2 inhibitors)

Docking and computing HPC support during Covid-19

https://covid19-hpc.mybluemix.net/


List of 100 programs for docking and virtual screening

https://www.vls3d.com/index.php/links/chemoinformatics/virtual-screening/structure-based-virtual-screening


XChem UK Diamond Light Source initiative

Contribute your expertise to design inhibitors of the SARS-CoV-2 main protease
https://covid.postera.ai/covid and
https://github.com/foldingathome/covid-moonshot


Crystal structure of PDB:6Y2G with bound ligand 13b

Ligand picture

Source: https://science.sciencemag.org/content/early/2020/03/20/science.abb3405