diff --git a/change/@fluentui-react-dd546ed0-e453-4f25-8149-7f3f79e30e17.json b/change/@fluentui-react-dd546ed0-e453-4f25-8149-7f3f79e30e17.json
new file mode 100644
index 00000000000000..28495c85b8016c
--- /dev/null
+++ b/change/@fluentui-react-dd546ed0-e453-4f25-8149-7f3f79e30e17.json
@@ -0,0 +1,7 @@
+{
+  "type": "patch",
+  "comment": "fix: Combobox adds aria-invalid when in an error state",
+  "packageName": "@fluentui/react",
+  "email": "sarah.higley@microsoft.com",
+  "dependentChangeType": "patch"
+}
diff --git a/packages/react/src/components/ComboBox/ComboBox.test.tsx b/packages/react/src/components/ComboBox/ComboBox.test.tsx
index cd1c4eb315c519..d87548b5081ab9 100644
--- a/packages/react/src/components/ComboBox/ComboBox.test.tsx
+++ b/packages/react/src/components/ComboBox/ComboBox.test.tsx
@@ -122,6 +122,15 @@ describe('ComboBox', () => {
     expect(combobox.getAttribute('aria-disabled')).toEqual('true');
   });
 
+  it('Sets aria-invalid when an error message is passed in.', () => {
+    const { getByRole, rerender } = render(<ComboBox errorMessage="error" options={DEFAULT_OPTIONS} />);
+    const combobox = getByRole('combobox');
+    expect(combobox.getAttribute('aria-invalid')).toEqual('true');
+
+    rerender(<ComboBox errorMessage={undefined} options={DEFAULT_OPTIONS} />);
+    expect(combobox.getAttribute('aria-invalid')).toBeNull();
+  });
+
   it('Renders no selected item in default case', () => {
     const { getByRole } = render(<ComboBox options={DEFAULT_OPTIONS} />);
     expect(getByRole('combobox').getAttribute('value')).toEqual('');
diff --git a/packages/react/src/components/ComboBox/ComboBox.tsx b/packages/react/src/components/ComboBox/ComboBox.tsx
index 8c4f9ce65d5146..f2b6da0d0d6811 100644
--- a/packages/react/src/components/ComboBox/ComboBox.tsx
+++ b/packages/react/src/components/ComboBox/ComboBox.tsx
@@ -659,6 +659,7 @@ class ComboBoxInternal extends React.Component<IComboBoxInternalProps, IComboBox
           aria-describedby={
             errorMessage !== undefined ? mergeAriaAttributeValues(ariaDescribedBy, errorMessageId) : ariaDescribedBy
           }
+          aria-invalid={errorMessage !== undefined ? 'true' : undefined}
           aria-activedescendant={ariaActiveDescendantValue}
           aria-required={required}
           aria-disabled={disabled}