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hemoncregimens.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://hemoncregimens.org/hemoncregimens#"
xml:base="http://hemoncregimens.org/hemoncregimens"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:obInOwl1="http://genenotology.org/formats/oboInOwl#"
xmlns:hemoncregimens="http://hemoncregimens.org/hemoncregimens">
<owl:Ontology rdf:about="http://hemoncregimens.org/hemoncregimens">
<owl:versionIRI rdf:resource="http://hemoncregimens.org/hemoncreigmens/v2023-09-11"/>
<owl:versionInfo>v2023-09-11</owl:versionInfo>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://hemoncregimens.org/hemoncregimens#HEMONC0000335 -->
<owl:AnnotationProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HEMONC0000335">
<rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<rdfs:label xml:lang="en">definition</rdfs:label>
</owl:AnnotationProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000003 -->
<owl:AnnotationProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000003">
<rdfs:label rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<rdfs:label xml:lang="en">dbxref</rdfs:label>
</owl:AnnotationProperty>
<!-- http://hemoncregimens.org/hemoncregimens#hasAge -->
<owl:AnnotationProperty rdf:about="http://hemoncregimens.org/hemoncregimens#hasAge"/>
<!-- http://hemoncregimens.org/hemoncregimens#hasDose -->
<owl:AnnotationProperty rdf:about="http://hemoncregimens.org/hemoncregimens#hasDose"/>
<!-- http://www.w3.org/2000/01/rdf-schema#comment -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#comment"/>
<!-- http://www.w3.org/2000/01/rdf-schema#isDefinedBy -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#isDefinedBy"/>
<!-- http://www.w3.org/2000/01/rdf-schema#label -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#label"/>
<!-- http://www.w3.org/2002/07/owl#versionInfo -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2002/07/owl#versionInfo"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Datatypes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://www.w3.org/1999/02/22-rdf-syntax-ns#PlainLiteral -->
<rdfs:Datatype rdf:about="http://www.w3.org/1999/02/22-rdf-syntax-ns#PlainLiteral"/>
<!-- http://www.w3.org/2001/XMLSchema#boolean -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#boolean"/>
<!-- http://www.w3.org/2001/XMLSchema#decimal -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#decimal"/>
<!-- http://www.w3.org/2001/XMLSchema#float -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#float"/>
<!-- http://www.w3.org/2001/XMLSchema#int -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#int"/>
<!-- http://www.w3.org/2001/XMLSchema#integer -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#integer"/>
<!-- http://www.w3.org/2001/XMLSchema#string -->
<rdfs:Datatype rdf:about="http://www.w3.org/2001/XMLSchema#string"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://hemoncregimens.org/hemoncregimens#HEMONC0000331 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HEMONC0000331">
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000077"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000057"/>
<rdfs:label xml:lang="en">hasStudyProtocol</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000121 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000121">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:label xml:lang="en">hasCourse</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000131 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000131">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000130"/>
<rdfs:label xml:lang="en">hasAnticancerMedication</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000132 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000132">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000130"/>
<rdfs:label xml:lang="en">hasLocalTherapyMedication</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000136 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000136">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000030"/>
<rdfs:label xml:lang="en">hasPhase</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000146 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000146">
<rdfs:label xml:lang="en">hasTreatment</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000147 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000147">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000146"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000068"/>
<rdfs:label xml:lang="en">hasMedicationAdministration</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000154 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000154">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000147"/>
<rdfs:label xml:lang="en">hasAnticancerMedicationAdministration</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000156 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000156">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000130"/>
<rdfs:label xml:lang="en">hasLocalTherapyMedicationAdministration</rdfs:label>
<rdfs:label xml:lang="en">hasSupportiveMedication</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000157 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000157">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000147"/>
<rdfs:label xml:lang="en">hasSupportiveMedicationAdministration</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000340 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000340">
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000077"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000020"/>
<rdfs:label xml:lang="en">hasAssociatedTreatmentLine</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens/0000120 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens/0000120">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000020"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000058"/>
<rdfs:label xml:lang="en">hasTreatmentExposure</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens/0000207 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens/0000207">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:label xml:lang="en">hasEligibleBiomarker</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens/0000295 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens/0000295">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000147"/>
<rdfs:label xml:lang="en">hasPreceedingMedicationAdministration</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregimens/0000296 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregimens/0000296">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000147"/>
<rdfs:label xml:lang="en">hasSubsequentMedicationAdministration</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000125 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000125">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000013"/>
<rdfs:label xml:lang="en">hasIntent</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000126 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000126">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000125"/>
<rdfs:label xml:lang="en">hasSupportiveIntent</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000127 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000127">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000125"/>
<rdfs:label xml:lang="en">hasSystemicCancerIntent</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000128 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000128">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000027"/>
<rdfs:label xml:lang="en">hasListProperty</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000129 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000129">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000128"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000027"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000027"/>
<rdfs:label xml:lang="en">isFollowedBy</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000130 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000130">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000067"/>
<rdfs:label xml:lang="en">hasMedication</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000133 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000133">
<rdfs:label xml:lang="en">hasNonCancerIntent</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000134 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000134">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000133"/>
<rdfs:label xml:lang="en">hasImmunoSuppressorIntent</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000135 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000135">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000127"/>
<rdfs:label xml:lang="en">hasAntiNeoPlasticIntent</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000137 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000137">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000136"/>
<owl:inverseOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000138"/>
<rdfs:label xml:lang="en">hasPriorPhase</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000138 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000138">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000136"/>
<rdfs:label xml:lang="en">hasSubsequentPhase</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000139 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000139">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:label xml:lang="en">hasPrognosis</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000140 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000140">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:label xml:lang="en">hasProtocol</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000141 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000141">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000057"/>
<rdfs:range>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000141"/>
<owl:someValuesFrom rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000048"/>
</owl:Restriction>
</rdfs:range>
<rdfs:label xml:lang="en">hasPublication</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000142 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000142">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000146"/>
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:label xml:lang="en">hasRegimen</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000143 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000143">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000142"/>
<owl:inverseOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000144"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:label xml:lang="en">hasPriorRegimen</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000144 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000144">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000142"/>
<rdfs:label xml:lang="en">hasSubsequentRegimen</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000148 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000148">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000146"/>
<rdfs:label xml:lang="en">hasPrimaryTreatment</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000149 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000149">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000146"/>
<rdfs:label xml:lang="en">hasSecondaryTreatment</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000150 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000150">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000146"/>
<rdfs:label xml:lang="en">hasProcedure</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000151 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000151">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000146"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000065"/>
<rdfs:label xml:lang="en">hasTreatmentComponent</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000153 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000153">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:range rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000029"/>
<rdfs:label xml:lang="en">hasTreatmentList</rdfs:label>
</owl:ObjectProperty>
<!-- http://hemoncregimens.org/hemoncregiments#HOR_0000155 -->
<owl:ObjectProperty rdf:about="http://hemoncregimens.org/hemoncregiments#HOR_0000155">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregiments#HOR_0000129"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000027"/>
<rdfs:label xml:lang="en">hasNext</rdfs:label>
</owl:ObjectProperty>
<!-- http://www.w3.org/2002/07/owl#topObjectProperty -->
<owl:ObjectProperty rdf:about="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Data properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000001 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000001">
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000048"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
<rdfs:label xml:lang="en">hasDOI</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000112 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000112">
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000068"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#decimal"/>
<rdfs:comment>Minimum of the age range for a given medication administartion.</rdfs:comment>
<rdfs:label>hasMinimumAge</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000114 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000114">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000440"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000068"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
<rdfs:comment>The number of days during which a medication is administered.</rdfs:comment>
<rdfs:label xml:lang="en">hasMedicationAdministrationDuration</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000115 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000115">
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#integer"/>
<rdfs:label xml:lang="en">hasIntervalBeforeNextTreatment</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000116 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000116">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topDataProperty"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
<rdfs:label xml:lang="en">hasName</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000117 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000117">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topDataProperty"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#boolean"/>
<rdfs:label xml:lang="en">hasPriorTherapy</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000118 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000118">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topDataProperty"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#int"/>
<rdfs:label>hasRepetitions</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000119 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000119">
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#boolean"/>
<rdfs:label xml:lang="en">isDeterminate</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000347 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000347">
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000068"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#float"/>
<rdfs:comment>Upper limit of the age range for a given medication administartion</rdfs:comment>
<rdfs:label xml:lang="en">hasMaximumAge</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000440 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000440">
<rdfs:label xml:lang="en">hasDuration</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000441 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000441">
<rdfs:subPropertyOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000440"/>
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000095"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
<rdfs:label xml:lang="en">hasRegimenDuration</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000442 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000442">
<rdfs:domain rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000068"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
<rdfs:label xml:lang="en">hasDose</rdfs:label>
</owl:DatatypeProperty>
<!-- http://hemoncregimens.org/hemoncregimens/0000164 -->
<owl:DatatypeProperty rdf:about="http://hemoncregimens.org/hemoncregimens/0000164">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topDataProperty"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
<rdfs:label xml:lang="en">hasCode</rdfs:label>
</owl:DatatypeProperty>
<!-- http://www.w3.org/2002/07/owl#topDataProperty -->
<owl:DatatypeProperty rdf:about="http://www.w3.org/2002/07/owl#topDataProperty"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://hemoncregimens.org/hemoncregimens#HORZ_0000438 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HORZ_0000438">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000071"/>
<rdfs:label xml:lang="en">Asparaginase (Elspar)</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000000 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000000">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000088"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000114"/>
<owl:hasValue>days1-5</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000442"/>
<owl:hasValue>0.60 m2 or more: 150 mg/m2 IV over 60 to 120 minutes once per day, Less than 0.60 m2: 5 mg/kg IV over 60 to 120 minutes once per day</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">EtoposideAdministration-HighDose</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_00000000000000000000 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_00000000000000000000">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000092"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000114"/>
<owl:hasValue>once</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000442"/>
<owl:hasValue>0.00-0.99 20; 1.00-1.99 30; 2.00-2.99 50; 3.00 or older 70</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">CytarabineAdministration-CNS-Prophylaxis-once</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000002 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000002">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000086"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000442"/>
<owl:hasValue>0.60 m2 or more: 100 mg/m2 IV over 1 to 30 minutes every 12 hours, Less than 0.60 m2: 3.3 mg/kg IV over 1 to 30 minutes every 12 hours</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">CytarabineAdministration-LowDose</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000004 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000004">
<HEMONC0000335>The type of cacner that has become neoplastic. Also referred to as morophology/behavior</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16681</HOR_0000003>
<rdfs:label xml:lang="en">Histology</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000005 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000005">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000004"/>
<HEMONC0000335>Carcinoma in situ</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2917</HOR_0000003>
<rdfs:label xml:lang="en">/2</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000006 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000006">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000004"/>
<HEMONC0000335>Malignant, primary site</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158874</HOR_0000003>
<rdfs:label xml:lang="en">/3</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000007 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000007">
<HEMONC0000335>" A characteristic that can be objectively measured and serves as an indicator for normal biologic processes, pathogenic processes, state of health or disease, the risk for disease development and/or prognosis, or responsiveness to a particular therapeutic intervention." from NCIt</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16342</HOR_0000003>
<rdfs:label xml:lang="en">Biomarker</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000008 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000008">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000007"/>
<rdfs:label xml:lang="en">FTL3_ITD+</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000009 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000009">
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000116"/>
<owl:someValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens/0000164"/>
<owl:someValuesFrom rdf:resource="http://www.w3.org/2001/XMLSchema#string"/>
</owl:Restriction>
</rdfs:subClassOf>
<HEMONC0000335>The clinical characterization of a patient's disease. Eventually should link somewhere appropriate to NCIt terms.</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15220</HOR_0000003>
<rdfs:comment>fix the url. how to constrains that it comes from NCIt, ICD-9-CM</rdfs:comment>
<rdfs:label xml:lang="en">Diagnosis</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000010 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000010">
<HEMONC0000335>A change in a patient's status with respect to treatment</HEMONC0000335>
<rdfs:label xml:lang="en">InflectionPoint</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000011 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000011">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000010"/>
<HEMONC0000335>"Not responding to treatment. " (NCIt)</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38014</HOR_0000003>
<rdfs:label xml:lang="en">Refractory</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000012 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000012">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000010"/>
<HEMONC0000335>Having reoccurred.</HEMONC0000335>
<rdfs:label xml:lang="en">Relapsed</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000013 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000013">
<HEMONC0000335>"An anticipated outcome that is the purpose for actions taken, thus guiding the' action." (NCIt)</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25725</HOR_0000003>
<rdfs:label xml:lang="en">Intent</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000014 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000014">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000013"/>
<HEMONC0000335>Treatment given when the intent is unclear is sometimes referred to as being given with borderline intent, following the concept of borderline surgical resectability. "Straddling the dividing line between two categories." (NCIt)</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14157</HOR_0000003>
<rdfs:label xml:lang="en">Borderline</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000015 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000015">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000013"/>
<HEMONC0000335>"A therapy designed to cure a condition." (NCIt)</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C185614</HOR_0000003>
<rdfs:label xml:lang="en">Curative</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000016 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000016">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000086"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000442"/>
<owl:hasValue>0.60 m2 or more: 1000 mg/m2 IV over 1 to 3 hours every 12 hours, Less than 0.60 m2: 33 mg/kg IV over 1 to 3 hours every 12 hours</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">CytarabineAdministration-HighDose-1</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000017 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000017">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000013"/>
<HEMONC0000335>Any action or response, without curative intent, that mitigates some or all of the unpleasant effects of a disease or condition.</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101516</HOR_0000003>
<rdfs:label xml:lang="en">Palliative</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000018 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000018">
<owl:equivalentClass rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000019"/>
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000013"/>
<HEMONC0000335>"Not stated explicitly or in detail." (NCIt)</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38046</HOR_0000003>
<rdfs:label xml:lang="en">Unclear</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000019 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000019">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000013"/>
<rdfs:label xml:lang="en">Unspecified</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000020 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000020">
<HEMONC0000335>"The sequence of therapies administered to a patient." (NCIt)</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133518</HOR_0000003>
<rdfs:label>Line</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000021 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000021">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000086"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000442"/>
<owl:hasValue>0.60 m2 or more: 3000 mg/m2 IV over 3 hours every 12 hours, Less than 0.60 m2: 100 mg/kg IV over 3 hours every 12 hours</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">CytarabineAdministration-HighDose-2</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000022 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000022">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000087"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000442"/>
<owl:hasValue>0.60 m2 or more: 50 mg/m2 IV over 1 to 15 minutes once per day, Less than 0.60 m2: 1.7 mg/kg IV over 1 to 15 minutes once per day</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">DaunorubicinAdministration-LowDose</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000023 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000023">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000089"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000442"/>
<owl:hasValue>0.60 m2 or more: 12 mg/m2 IV over 15 to 30 minutes once per day, Less than 0.60 m2: 0.4 mg/kg IV once per day</owl:hasValue>
</owl:Restriction>
</rdfs:subClassOf>
<rdfs:label xml:lang="en">MitoxantroneAdministration-LowDose</rdfs:label>
</owl:Class>
<!-- http://hemoncregimens.org/hemoncregimens#HOR_0000024 -->
<owl:Class rdf:about="http://hemoncregimens.org/hemoncregimens#HOR_0000024">
<rdfs:subClassOf rdf:resource="http://hemoncregimens.org/hemoncregimens#HOR_0000020"/>
<HEMONC0000335>"The second preferred therapy for a particular condition, used after first-line treatment fails or if a person cannot tolerate first-line drugs." (NCIt)</HEMONC0000335>
<HOR_0000003>http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54350</HOR_0000003>
<rdfs:label xml:lang="en">Second-Line</rdfs:label>
</owl:Class>