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Data

Stage: Theiler 21 (E12.5):

Stage: Theiler 24 (E16):

--This does not have any surfaces in the STL format!--

Stage: Theiler 25 (E17.0):

--This one is used for the screenshot below--

Models for almost all other stages of mouse development are available here

Organs needed & provided

  • Lung (provided by emouse)
  • Ovary (not provided by emouse)
  • Muscle (not provided by emouse)
  • Kidney (provided by emouse)
  • Pancreas (provided by emouse)

Four STL files were provided, see here.

Screenshot of all three in one Blender scene (from Stage: Theiler 25 [E17.0]), see metadata here:

A screenshot of a Blender scene with lung, pancreas, and kidney_pelvis loaded

Related Paper

From https://www.researchgate.net/figure/Large-scale-structure-of-the-mouse-lung-The-right-lung-has-4-lobes-and-the-left-lung-has_fig8_276464605

Figure 1 from https://www.researchgate.net/publication/276464605_Scale_Dependence_of_Structure-Function_Relationship_in_the_Emphysematous_Mouse_Lung

3D Models and Registration

Lung

Update 2/18/25

All seven 5x5 tissue blocks (registration by Andreas Bueckle and Sojin Kim)

7 blocks positioned, the team receives the lung tissues only from JAX.

Update 10/28/24: Adjusted positions for IHC (left middle) and unbiased (right), removed 2 from left lobe.

A screenshot of the lung with arrows for extraction sites A second screenshot of the lung with arrows for extraction sites, dorsal view

Pancreas

Team is unsure who will handle pancreas registrations

Kidney

Team has no information

Team will reach out to 5x5 team, who will provide information for kidney and pancreas

Ovary

Need reference organ and collaborators

Muscle

Need reference organ and collaborators