wtd2_params.txt

cai0_ca_ion = 0.001		
cao0_ca_ion = 5			
cali0_cal_ion = 0.001		
calo0_cal_ion = 5			
#celsius = 34			

global_ra = 100		# not really sure what this is
RA = 100			# ohm-cm - constant for whole cell
CM = 1				# uF-cm2 - constant for whole cell
G_PAS = 1.15e-5			# S/cm2
E_PAS = -70			# mV

G_NAF = 1.5		# soma only
G_NAFD = 0.0195	# all dends
G_NAP = 4e-5		# soma only
G_NAPD = 1.3802e-7	# all dends, according to Wolf et al. paper
#G_NAPD = 1.3802e-6	# all dends -- CHANGED in Wolf modelDB entry

G_KIR = 0.00014		# S/cm2
G_KAS = 0.0104		# soma & prox dends; s/cm2
G_KASD = 0.00095142	# mid & distal dends; S/cm2
G_KAF = 0.0225 		# soma & prox dends; S/cm2
G_KAFD = 0.020584	# mid & dist dends; S/cm2
G_BKKCA = 0.001		# 
G_SKKCA = 0.145
G_KDR = 0.00604
G_KDR_AIS = 0.00604

G_NAF_AIS = 1.5		# different values allowed in axon initial segment
G_KAS_AIS = 0.0104
G_KAF_AIS = 0.0225
G_NAP_AIS = 4e-5

CAINF = 1e-5			# mM, steady state intracell ca conc.
TAUR = 43			# ms, time const of ca diffusion - Jackson 2003
CA_DRIVE = 10000
CA_PUMP = 0.02

caNMDA = 0.1
P_CAL = 6.7e-6			# cm/s
P_CALD = 6.7e-6			# cm/s
P_CAL13 = 4.25e-7		#1.7e-6		# cm/s
P_CAL13D = 4.25e-7		#1.7e-6		# cm/s
P_CAN = 0.000019383			# cm/s
P_CAQ = 6.0e-6			# cm/s
P_CAR = 0.0000380846			# cm/s
P_CAT = 0.0000005982		# cm/s	4e-7

EK = -94
ENA = 50

HSHIFT_NAP = -10
MSHIFT_NAP = -10
MSHIFT_KAS = 2
HSHIFT_KAS = 22.5
MSHIFT_KAF = 0
HSHIFT_KAF = 0
HTAUSHIFT_KAS = -90

M1HALF_BK = -10
M2HALF_BK = -65
M3HALF_BK = -44
CELSIUS_SK_SKKCA = 22

NET_N = 1e10

G_AMPA = 8.5e-4		#350e-6		#8.81e-4
G_NMDA = 12.2e-5	# 9.2e-5	
G_GABA = 0.0021		#4300e-6	#0.0027

AMPA_WT = 1
NMDA_WT = 1
GABA_WT = 1

NOISE = 1

NGLU = 84
NGABA = 84
NSYN = NGABA + NGLU

# factors for adding the Hay axon
CM_MYELINFAC = 0.02		# Hay myelin had cm=0.02, cm=1 in AIS/soma
AXON_MSHIFT  = 10
AXON_HSHIFT  = 5
AXON_MSLOPEFAC = 1.29		# Hay NaT m_slope was 9/mV in axon, 7/mV in soma
SOMA_MVHALF_NAF = -23.9
SOMA_MSLOPE_NAF = -11.8
SOMA_MSHIFT_NAF = 0
SOMA_HVHALF_NAF = -62.9
SOMA_HSLOPE_NAF = 10.7
SOMA_HSHIFT_NAF = 0

G_PAS = 0.0000565446
E_PAS = -76.9443641966
CM    = 0.900001
G_KIR = 0.0136006786
QKIR  = 0.200000
SHKIR = 101.340908321
SLPKIR = 11.8894574774

V0 = -80
v_init=-80
P_CAQ = 0			# cm/s - turn this off, Evans excluded it.

      # note, we will include NaP in this optimization due to the axon inclusion.